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Developing a mechanistic in vitro-in vivo relationship (IVIVR) for drug A using Physiologically-based pharmacokinetic modeling
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Development of a kidney transporter-mediated drug-drug interaction between cimetidine (perpetrator) and ranitidine (substrate) using PBPK modeling
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A PBPK model-based drug interaction study to inform the dose selection of a new compound
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Translational PK of bevacizumab between monkey and human using PBPK modeling
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Prediction of target-mediated PK profile of Bevacizumab in cancer patients using PBPK modeling
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Development of a mechanistic absorption model for a monoclonal antibody administered subcutaneously
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