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Developing a mechanistic in vitro-in vivo relationship (IVIVR) for drug A using Physiologically-based pharmacokinetic modeling

Developing a mechanistic in vitro-in vivo relationship (IVIVR) for drug A using Physiologically-based pharmacokinetic modeling

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Development of a kidney transporter-mediated drug-drug interaction between cimetidine (perpetrator) and ranitidine (substrate) using PBPK modeling

Development of a kidney transporter-mediated drug-drug interaction between cimetidine (perpetrator) and ranitidine (substrate) using PBPK modeling

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