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Drug-drug interaction simulation study: FIM trial optimization

How to design an optimized Phase I clinical trial knowing that the drug candidate will potentially interact with another drug during patient treament.

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Early prediction of final drug posology

How Modeling and Simulation can help to have early information about the dose to test in further clinical trial studies

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Animal PBPK models: extrapolation for Human

How preclinical results can be used to strengthen the efficacy of phase I clinical trial

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